Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular ...

Although zinc fingers are best known to interact with DNA, they can, as in the case of the TFIIIA protein, also interact with RNA. A recent crystal structure reveals that zinc fingers can take ...

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

As a molecular biologist, I always enjoy reading articles concerning DNA and RNA. Your excellent article in the April 3, 2023, issue of C&EN (page 18) titled “The Promise of Peptide Nucleic Acids” ...

The discovery of DNA structure by James Watson and Francis Crick in the year 1953 is one of the most revolutionary scientific discoveries to date. However, the research leading to the discovery of ...

In this edition of the biotech bi-weekly, we highlight the latest exciting product launches, partnerships and company events.

A loss of TET enzymes, which demethylate DNA, may cause cancer. In TET deficient mice, DNA forms strange structures called G-quadruplexes (G4s) and R-loops that may drive cancer development, a ...

Researchers have developed intranasal spherical nucleic acids that activate the cGAS–STING pathway and reprogram the ...

Explore how the YB1 protein's intrinsic disorder helps it perform crucial cellular functions, impacting cancer therapies.

Around 80% of proteins involved in diseases like cancer and neurodegenerative illnesses do not have a stable structure. These proteins, known as intrinsically disordered proteins (IDPs) can quickly ...