Predictions, picks and odds for NFL Week 15 game

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Week 15 NFL picks, odds, best bets from proven model: This 5-leg parlay pays nearly 25-1
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 15 on a 50-35 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

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Browns at Bears: Predictions, picks and odds for NFL Week 15 game
SportsLine · 14h
NFL odds, lines, spreads: 2025 Week 15 picks, predictions from proven model
Bills focus on themselves, not defending their AFC East title that's on the line against New England
For Bills left tackle Dion Dawkins, the expectation of winning at New England on Sunday is more important than the motivation to prevent the Patriots from wrenching the AFC East title away from Buffal...

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Drake Maye, Stefon Diggs React to Patriots Being Home Underdogs to Josh Allen, Bills
Bills at Patriots: 5 things to watch for during Week 15 game
Patriots can clinch playoff berth and AFC East title with win over Bills
Matt Bowen explains why fantasy managers should consider starting Jauan Jennings in Week 15.

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Bills at Patriots: 5 storylines to watch for during lead up to Week 15
How the Patriots can clinch AFC East title, playoff berth

Self-learning AI releases NFL picks, score predictions every Week 15 game

Before making any Week 15 NFL picks or NFL score predictions on those games or others, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI.

Best DFS picks for Falcons at Buccaneers in Week 15

Nick Simon brings you his favorite picks for FanDuel’s Thursday night single-game DFS contests.

NFL playoff odds entering Week 15: Every AFC, NFC team's chances

Here's a look at how the sportsbooks view each NFL team's chances of reaching the playoffs in 2025 before Week 15 kicks off and the playoff picture.

NFL Week 15 picks: Our experts break down Packers-Broncos, Patriots-Bills and a loaded Sunday slate

This week in the NFL, we get a rematch of Bills vs. New England Patriots, Jordan Love travels to take on one of the best defenses in the NFL in the Denver Broncos, while the " Matthew Stafford Bowl" takes place in Los Angeles.
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